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Peer-Reviewed Publications

1. Parkins KM, Krishnamachary B, Jacob D, Kakkad S, Solaiyappan M, Mishra A, Mironchik Y, Penet MF,

McMahon MT, Knopf P, Pichler BJ, Nimmagadda N, Bhujwalla ZM. PET/MRI and Bioluminescence

Imaging Identify Hypoxia as a Cause of PD-L1 Expression Heterogeneity Radiology-Imaging Cancer.

2023;in press.

2. Penet MF, Sharma RK, Bharti S, Mori N, Artemov D, Bhujwalla ZM. Cancer insights from magnetic

resonance spectroscopy of cells and excised tumors. NMR Biomed. 2023;36(4):e4724. Epub

2022/03/10. doi: 10.1002/nbm.4724. PubMed PMID: 35262263; PubMed Central PMCID:


3. Mori N, Jin J, Krishnamachary B, Mironchik Y, Wildes F, Vesuna F, Barnett JD, Bhujwalla ZM. Functional

roles of FAP-alpha in metabolism, migration and invasion of human cancer cells. Front Oncol.

2023;13:1068405. Epub 2023/03/21. doi: 10.3389/fonc.2023.1068405. PubMed PMID: 36937451;

PubMed Central PMCID: PMCPMC10015381.

4. Jin J, Barnett JD, Krishnamachary B, Mironchik Y, Luo CK, Kobayashi H, Bhujwalla ZM. Evaluating nearinfrared

photoimmunotherapy for targeting fibroblast activation protein-alpha expressing cells in vitro and

in vivo. Cancer Sci. 2023;114(1):236-46. Epub 2022/09/29. doi: 10.1111/cas.15601. PubMed PMID:

36169301; PubMed Central PMCID: PMCPMC9807523.

5. Goggins E, Mironchik Y, Kakkad S, Jacob D, Wildes F, Bhujwalla ZM, Krishnamachary B.

Reprogramming of VEGF-mediated extracellular matrix changes through autocrine signaling. Cancer

Biology and Therapy. 2023;24(1).

6. Tan S, Chen Z, Mironchik Y, Mori N, Penet MF, Si G, Krishnamachary B, Bhujwalla ZM. VEGF

Overexpression Significantly Increases Nanoparticle-Mediated siRNA Delivery and Target-Gene

Downregulation. Pharmaceutics. 2022;14(6). Epub 2022/06/25. doi: 10.3390/pharmaceutics14061260.

PubMed PMID: 35745832; PubMed Central PMCID: PMCPMC9229257.

7. Jin J, Sivakumar I, Mironchik Y, Krishnamachary B, Wildes F, Barnett JD, Hung CF, Nimmagadda S,

Kobayashi H, Bhujwalla ZM, Penet MF. PD-L1 near Infrared Photoimmunotherapy of Ovarian Cancer

Model. Cancers (Basel). 2022;14(3). Epub 2022/02/16. doi: 10.3390/cancers14030619. PubMed PMID:

35158887; PubMed Central PMCID: PMCPMC8833482.

8. Chen Z, Krishnamachary B, Mironchik Y, Ray Banerjee S, Pomper MG, Bhujwalla ZM. PSMA-specific

degradable dextran for multiplexed immunotargeted siRNA therapeutics against prostate cancer.

Nanoscale. 2022;14(38):14014-22. Epub 2022/09/13. doi: 10.1039/d2nr02200a. PubMed PMID:

36093754; PubMed Central PMCID: PMCPMC9844541.

9. Barnett JD, Jin J, Penet MF, Kobayashi H, Bhujwalla ZM. Phototheranostics of Splenic Myeloid-Derived

Suppressor Cells and Its Impact on Spleen Metabolism in Tumor-Bearing Mice. Cancers (Basel).

2022;14(15). Epub 2022/07/28. doi: 10.3390/cancers14153578. PubMed PMID: 35892836; PubMed

Central PMCID: PMCPMC9332589.

10. Pacheco-Torres J, Penet MF, Mironchik Y, Krishnamachary B, Bhujwalla ZM. The PD-L1 metabolic

interactome intersects with choline metabolism and inflammation. Cancer Metab. 2021;9(1):10. Epub

2021/02/21. doi: 10.1186/s40170-021-00245-w. PubMed PMID: 33608051; PubMed Central PMCID:


11. Ngen EJ, Chen Y, Azad BB, Boinapally S, Jacob D, Lisok A, Shen C, Hossain MS, Jin J, Bhujwalla ZM,

Pomper MG, Banerjee SR. Prostate-specific membrane antigen (PSMA)-targeted photodynamic therapy

enhances the delivery of PSMA-targeted magnetic nanoparticles to PSMA-expressing prostate tumors.

Nanotheranostics. 2021;5(2):182-96. Epub 2021/02/11. doi: 10.7150/ntno.52361. PubMed PMID:

33564617; PubMed Central PMCID: PMCPMC7868004.

12. Vagal A, Reeder SB, Sodickson DK, Goh V, Bhujwalla ZM, Krupinski EA. The Impact of the COVID-19

Pandemic on the Radiology Research Enterprise: Radiology Scientific Expert Panel. Radiology.

2020;296(3):E134-E40. Epub 2020/04/16. doi: 10.1148/radiol.2020201393. PubMed PMID: 32293224;

PubMed Central PMCID: PMCPMC7233405.


13. Penet MF, Kakkad S, Wildes F, Bhujwalla ZM. Water and Collagen Content Are High in Pancreatic

Cancer: Implications for Quantitative Metabolic Imaging. Front Oncol. 2020;10:599204. Epub

2021/02/16. doi: 10.3389/fonc.2020.599204. PubMed PMID: 33585215; PubMed Central PMCID:



14. Pacheco-Torres J, Penet MF, Krishnamachary B, Mironchik Y, Chen Z, Bhujwalla ZM. PD-L1 siRNA

Theranostics With a Dextran Nanoparticle Highlights the Importance of Nanoparticle Delivery for Effective

Tumor PD-L1 Downregulation. Front Oncol. 2020;10:614365. Epub 2021/03/16. doi:

10.3389/fonc.2020.614365. PubMed PMID: 33718115; PubMed Central PMCID: PMCPMC7947807.


15. Krishnamachary B, Mironchik Y, Jacob D, Goggins E, Kakkad S, Ofori F, Dore-Savard L, Bharti SK,

Wildes F, Penet MF, Black ME, Bhujwalla ZM. Hypoxia theranostics of a human prostate cancer xenograft

and the resulting effects on the tumor microenvironment. Neoplasia. 2020;22(12):679-88. Epub

2020/11/04. doi: 10.1016/j.neo.2020.10.001. PubMed PMID: 33142234; PubMed Central PMCID:



16. Chen Z, Krishnamachary B, Pachecho-Torres J, Penet MF, Bhujwalla ZM. Theranostic small interfering

RNA nanoparticles in cancer precision nanomedicine. Wiley Interdiscip Rev Nanomed Nanobiotechnol.

2020;12(2):e1595. Epub 2019/10/24. doi: 10.1002/wnan.1595. PubMed PMID: 31642207; PubMed

Central PMCID: PMCPMC7360334.


17. Kakkad S, Krishnamachary B, Jacob D, Pacheco-Torres J, Goggins E, Bharti SK, Penet MF, Bhujwalla

ZM. Molecular and functional imaging insights into the role of hypoxia in cancer aggression. Cancer

Metastasis Rev. 2019;38(1-2):51-64. Epub 2019/03/07. doi: 10.1007/s10555-019-09788-3. PubMed

PMID: 30840168; PubMed Central PMCID: PMCPMC6625878.


18. Jin J, Krishnamachary B, Barnett JD, Chatterjee S, Chang D, Mironchik Y, Wildes F, Jaffee EM,

Nimmagadda S, Bhujwalla ZM. Human Cancer Cell Membrane-Coated Biomimetic Nanoparticles

Reduce Fibroblast-Mediated Invasion and Metastasis and Induce T-Cells. ACS Appl Mater Interfaces.

2019;11(8):7850-61. Epub 2019/02/02. doi: 10.1021/acsami.8b22309. PubMed PMID: 30707559;

PubMed Central PMCID: PMCPMC6628902.


19. Jin J, Bhujwalla ZM. Biomimetic Nanoparticles Camouflaged in Cancer Cell Membranes and Their

Applications in Cancer Theranostics. Front Oncol. 2019;9:1560. Epub 2020/02/11. doi:

10.3389/fonc.2019.01560. PubMed PMID: 32039028; PubMed Central PMCID: PMCPMC6985278.


20. Bharti SK, Kakkad S, Danhier P, Wildes F, Penet MF, Krishnamachary B, Bhujwalla ZM. Hypoxia Patterns

in Primary and Metastatic Prostate Cancer Environments. Neoplasia. 2019;21(2):239-46. Epub

2019/01/15. doi: 10.1016/j.neo.2018.12.004. PubMed PMID: 30639975; PubMed Central PMCID:



21. Krishnamachary B, Danhier P, Kakkad S, Bharti SK, Bhujwalla ZM. Hypoxia-Induced Reporter Genes

with Different Half-Lives. Methods Mol Biol. 2018;1790:113-25. Epub 2018/06/03. doi: 10.1007/978-1-

4939-7860-1_9. PubMed PMID: 29858787; PubMed Central PMCID: PMCPMC7990048.


22. Chen Z, Krishnamachary B, Penet MF, Bhujwalla ZM. Acid-degradable Dextran as an Image Guided

siRNA Carrier for COX-2 Downregulation. Theranostics. 2018;8(1):1-12. Epub 2018/01/02. doi:

10.7150/thno.21052. PubMed PMID: 29290789; PubMed Central PMCID: PMCPMC5743456.


23. Bhujwalla ZM, Kakkad S, Chen Z, Jin J, Hapuarachchige S, Artemov D, Penet MF. Theranostics and

metabolotheranostics for precision medicine in oncology. J Magn Reson. 2018;291:141-51. Epub

2018/05/01. doi: 10.1016/j.jmr.2018.03.004. PubMed PMID: 29705040; PubMed Central PMCID:


Book Chapters
1. Penet M-F and Bhujwalla ZM. High-Resolution 1H MRS Metabolomics of Biofluids in Cancer. European
Biophysical Societies’ Association, 2022.

2. Penet M-F, Kakkad S, Pacheco-Torres J, Bharti S, Krishnamachary, Bhujwalla ZM. Molecular and Functional
Imaging and Theranostics of the Tumor Microenvironment. In: Molecular Imaging: Principles and Practice, 2nd
Edition, Academic Press, 2021.

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