Peer-Reviewed Articles
57. Coughlin JM, Slania S, Du Y, Shinehouse LK, Brosnan MK, Azad BB, Holt DP, Fan H, Lesniak WG, Minn I, Rowe SP, Dannals RF, Horti AG, Pomper MG. First-in-human neuroimaging of soluble epoxide hydrolase using [18F]FNDP PET. Eur J Nucl Med Mol Imaging. 2021 Sep;48(10):3122-3128. doi: 10.1007/s00259-021-05231-4.
56. Du Y, Minn I, Foss C, Lesniak WG, Hu F, Dannals RF, Pomper MG, Horti AG. PET imaging of soluble
epoxide hydrolase in non-human primate brain with [18F]FNDP. EJNMMI Res. 2020 Jun 22;10(1):67. doi:
10.1186/s13550-020-00657-7.
55. Du Y, Coughlin JM, Brosnan MK, Chen A, Shinehouse LK, Abdallah R, Lodge MA, Mathews WB, Liu C, Wu Y, Minn I, Finley P, Hall AW, Lesniak WG, Dannals RF, Horti AG, Pomper MG. First-in-human
imaging using [11C]MDTC: a radiotracer targeting the cannabinoid receptor type 2. Eur J Nucl Med Mol
Imaging. 2023 Mar 6. doi: 10.1007/s00259-023-06170-y.
54. Leung KH, Rowe SP, Leal JP, Ashrafinia S, Sadaghiani MS, Chung HW, Dalaie P, Tulbah R, Yin Y,
VanDenBerg R, Werner RA, Pienta KJ, Gorin MA, Du Y, Pomper MG. Deep learning and radiomics
framework for PSMA-RADS classification of prostate cancer on PSMA PET. EJNMMI Res. 2022 Dec
29;12(1):76. doi: 10.1186/s13550-022-00948-1.
53. Coughlin JM, Du Y, Lesniak WG, Harrington CK, Brosnan MK, O'Toole R, Zandi A, Sweeney SE,
Abdallah R, Wu Y, Holt DP, Hall AW, Dannals RF, Solnes L, Horti AG, Pomper MG. First-in-human use
of 11C-CPPC with positron emission tomography for imaging the macrophage colony-stimulating factor
1 receptor. EJNMMI Res. 2022 Sep 30;12(1):64. doi: 10.1186/s13550-022-00929-4.
52. Levinstein MR, Ventriglia EN, Gomez JL, Budinich RC, Marton J, Henriksen G, Holt DP, Dannals RF,
Pomper MG, Zarate CA Jr, Bonaventura J, Michaelides M. 6-O-(2-[18F]Fluoroethyl)-6-O-Desmethyl-
Diprenorphine ([18F]FE-DPN) Preferentially Binds to Mu Opioid Receptors In Vivo. Mol Imaging Biol. 2023
Apr;25(2):384-390. doi: 10.1007/s11307-022-01767-5.
51. Cheng B, Ahn HH, Nam H, Jiang Z, Gao FJ, Minn I, Pomper MG. A Unique Core-Shell Structured, Glycol Chitosan-Based Nanoparticle Achieves Cancer-Selective Gene Delivery with Reduced Off-Target Effects. Pharmaceutics. 2022 Feb 7;14(2):373. doi: 10.3390/pharmaceutics14020373.
50. Zhou X, Jiang J, Yang X, Liu T, Ding J, Nimmagadda S, Pomper MG, Zhu H, Zhao J, Yang Z, Li N. First-in-Humans Evaluation of a PD-L1-Binding Peptide PET Radiotracer in Non-Small Cell Lung Cancer
Patients. J Nucl Med. 2022 Apr;63(4):536-542. doi: 10.2967/jnumed.121.262045.
49. Koshino K, Werner RA, Pomper MG, Bundschuh RA, Toriumi F, Higuchi T, Rowe SP. Narrative review
of generative adversarial networks in medical and molecular imaging. Ann Transl Med. 2021 May;9(9):821. doi: 10.21037/atm-20-6325.
48. Liu HW, Hu Y, Ren Y, Nam H, Santos JL, Ng S, Gong L, Brummet M, Carrington CA, Ullman CG, Pomper MG, Minn I, Mao HQ. Scalable Purification of Plasmid DNA Nanoparticles by Tangential Flow Filtration for Systemic Delivery. ACS Appl Mater Interfaces. 2021 Jul 7;13(26):30326-30336. doi: 10.1021/acsami.1c05750.
47. Sadaghiani MS, Sheikhbahaei S, Werner RA, Pienta KJ, Pomper MG, Solnes LB, Gorin MA, Wang NY,
Rowe SP. A Systematic Review and Meta-analysis of the Effectiveness and Toxicities of Lutetium-177-
labeled Prostate-specific Membrane Antigen-targeted Radioligand Therapy in Metastatic Castration-
Resistant Prostate Cancer. Eur Urol. 2021 Jul;80(1):82-94. doi: 10.1016/j.eururo.2021.03.004.
46. Vaidyanathan G, Mease RC, Minn I, Choi J, Chen Y, Shallal H, Kang CM, McDougald D, Kumar V,
Pomper MG, Zalutsky MR. Synthesis and preliminary evaluation of 211At-labeled inhibitors of prostatespecific
membrane antigen for targeted alpha particle therapy of prostate cancer. Nucl Med Biol. 2021
Mar-Apr;94-95:67-80. doi: 10.1016/j.nucmedbio.2021.01.002.
45. Ngen EJ, Chen Y, Azad BB, Boinapally S, Jacob D, Lisok A, Shen C, Hossain MS, Jin J, Bhujwalla ZM,
Pomper MG, Banerjee SR. Prostate-specific membrane antigen (PSMA)-targeted photodynamic therapy
enhances the delivery of PSMA-targeted magnetic nanoparticles to PSMA-expressing prostate tumors.
Nanotheranostics. 2021 Jan 19;5(2):182-196. doi: 10.7150/ntno.52361.
44. Hu F, Morris PJ, Bonaventura J, Fan H, Mathews WB, Holt DP, Lam S, Boehm M, Dannals RF, Pomper MG, Michaelides M, Horti AG. Eur J Med Chem. 2021 Mar 5;213:113047. doi:
10.1016/j.ejmech.2020.113047.
43. Rowe, S. P., Pomper, M. G. (2021) Molecular imaging in oncology: current impact and future directions.
CA Cancer J Clin caac.21713
42. Hapuarachchige, S. Si, G., Huang, C. T., Lesniak, W. G., Mease, R., Guo, X., Gabrielson, K., Artemov,
D. (2021) Dual-modality PET-SPECT image-guided pretargeting delivery in HER2(+) breast cancer
models. Biomacromolecules 22, 4606-4617
41. Kumar D, Mishra A, Lisok A, Kureshi R, Shelake S, Plyku D, Sen R, Doucet M, De Silva RA, Mease RC,
Forde PM, Jaffee EM, Desai P, Ganguly S, Gabrielson E, Vaidya D, Spangler JB, Nimmagadda S.
Pharmacodynamic measures within tumors expose differential activity of PD(L)-1 antibody therapeutics.
Proc Natl Acad Sci U S A. 2021 Sep14;118(37):e2107982118. PMID: 34508005
40. Leung K. H., Rowe, S. P., Pomper, M. G., Du, Y. A three-stage, deep learning, ensemble approach for
prognosis in patients with Parkinson’s disease. (2021) EJNMMI Res 11, 52
39. Mease, R. C., Kang, C. M., Kumar, V., Banerjee, S. R., Minn, I., Brummet, M., Gabrielson, K. L., Feng,
Y., Park, A., Kiess, A. P., Sgouros, G., Vaidyanathan, G., Zalutsky, M. R., Pomper, M. G. (2021) An
improved 211At-labeled agent for PSMA-targeted alpha therapy. J Nucl Med jnumed.121.262098
38. Khatri W., Chung H. W., Werner, R. A., Leal, J. P., Pienta, K. J., Lodge, M. A., Gorin, M. A., Pomper, M.G., Rowe, S. P. (2021) Effect of point-spread function reconstruction for indeterminate PSMA-RADS-3A
lesions on PSMA-targeted PET imaging of men with prostate cancer. Diagnostics 11, 665
37. Ordonez, A. A., Wintaco, L. M., Mota, F., Restrepo, A. F., Ruiz-Bedoya, C. A., Reyes, C. F., Uribe, L. G.,
Abhishek, S., D’Alessio, F. R., Holt, D. P., Dannals, R. F., Rowe, S. P., Castillo, V. R., Pomper, M. G.,
Granados, U., Jain, S. K. (2021) Imaging Enterobacterales infections in patients using pathogen-specific
positron emission tomography. Sci Transl Med 13, scitranslmed.abe9805
36. Sadaghiani, M. S., Sheikhbahaei, S., Werner, R. A., Pienta, K. J., Pomper, M. G., Solnes, L. B., Gorin,
M. A., Rowe, S. P. (2021) A systematic review and meta-analysis of the effectiveness and toxicities of
lutetium-177-labeled prostate-specific membrane antigen-targeted radioligand therapy in metastatic
castration-resistant prostate cancer. Eur Urol 80, 82-94
35. Slania, S. L., Das, D., Lisok, A., Du, Y., Jiang, Z., Mease, R. C., Rowe, S. P., Nimmagadda, S., Yang, X.,
Pomper, M. G. (2021) Imaging of fibroblast activation protein in cancer xenografts using novel (4-
quinolinoyl)-glycyl-2-cyanopyrrolidine-based small molecules. J Med Chem 64, 4059-4070
34. Vaidyanathan, G., Kang, C. M., McDougald, D., Minn, I., Brummet, M., Pomper, M. G., and Zalutsky, M.
R. (2018) Brush border enzyme-cleavable linkers: Evaluation for reducing renal uptake of radiolabeled
prostate-specific membrane antigen inhibitors. Nucl Med Biol 62-63, 18-30
33. De Silva, R., Gorin, M. A., Mease, R. C., Minn, I., Lisok, A., Plyku, D., Nimmagadda, S., Allaf, M. E.,
Yang, X., Sgouros, G., Rowe, S. P., Pomper, M.G. (2021) Process validation, cGMP production,
dosimetry, and toxicity studies of the CAIX imaging agent [111In]In-XYIMSR-01 for phase I regulatory
approval. J Labelled Comp Radiopharm 64, 243-250
32. Ngen, E. J., Benham Azad, B., Boinapally, S., Lisok, A., Brummet, M., Jacob, D., Pomper, M. G., and
Banerjee, S. R. (2019) MRI Assessment of Prostate-Specific Membrane Antigen (PSMA) Targeting by a
PSMA-Targeted Magnetic Nanoparticle: Potential for Image-Guided Therapy. Mol Pharm 16, 2060-2068
31. Gomez, J. L., Bonaventura, J., Lesniak, W., Mathews, W. B., Sysa-Shah, P., Rodriguez, L. A., Ellis, R.
J., Richie, C. T., Harvey, B. K., Dannals, R. F., Pomper, M. G., Bonci, A., and Michaelides, M. (2017)
Chemogenetics revealed: DREADD occupancy and activation via converted clozapine. Science 357,
503-507
30. Ray, S., Lisok, A., Minn, I, Josefsson, A., Kumar, V., Brummet, M., Boinapally, S., Brayton, C., Mease,
R. C., Sgouros, G., Hobbs, R. F., Pomper, M. G. (2021) Preclinical evaluation of 213Bi-/225Ac-labeled low molecular-weight compounds for radiopharmaceutical therapy of prostate cancer. J Nucl Med 62 980-988
29. Nimmagadda S. Quantifying PD-L1 Expression to Monitor Immune Checkpoint Therapy: Opportunities
and Challenges. Cancers (Basel). 2020 Oct 29;12(11):3173. PMID: 33137949
28. Santhanam, P. Russell, J., Rooper, L. M., Ladenson, P. W., Pomper, M. G., Rowe, S. P. (2020) The
prostate-specific membrane antigen (PSMA)-targeted radiotracer 18F-DCFPyL detects tumor
neovasculature in metastatic, advanced, radioiodine-refractory, differentiated thyroid cancer. Med Oncol
37, 98
27. Huang, C. T., Guo, X., Barinka, C., Lupold, S. E., Pomper, M. G., Gabrielson, K., Raman, V., Artemov,
D., and Hapuarachchige, S. (2020) Development of 5D3-DM1: A Novel Anti-Prostate-Specific Membrane
Antigen Antibody-Drug Conjugate for PSMA-Positive Prostate Cancer Therapy. Mol Pharm 17, 3392-
3402
26. Plavén-Sigray, P., Matheson, G. J., Coughlin, J. M., Hafizi, S., Laurikainen, H., Ottoy, J., De Picker, L.,
Rusjan, P., Hietala, J., Howes, O. D., Mizrahi, R., Morrens, M., Pomper, M. G., and Cervenka, S. (2021)
Meta-analysis of the Glial Marker TSPO in Psychosis Revisited: Reconciling Inconclusive Findings of
Patient-Control Differences. Biol Psychiatry 89, e5-e8
25. Leung, K. H., Marashdeh, W., Wray, R., Ashrafinia, S., Pomper, M. G., Rahmim, A., and Jha, A. K. (2020)
A physics-guided modular deep-learning based automated framework for tumor segmentation in PET.
Phys Med Biol 65, 245032
24. Werner, R. A., Derlin, T. Lapa, C., Sheikbahaei, S., Higuchi, T., Giesel, F. L., Behr, S., Drzezga, A.,
Kimura, H., Buck, A. K., Derlin, T., Bengel, F. M., Pomper, M. G., Gorin, M. A., Rowe, S. P. (2020) 18F-Labeled, PSMA-targeted radiotracers: leveraging the advantages of radiofluorination for prostate cancer
molecular imaging. Theranostics 10, 1-16
23. Hapuarachchige, S., Huang, C. T., Donnelly, M. C., Barinka, C., Lupold, S. E., Pomper, M. G., and
Artemov, D. (2020) Cellular Delivery of Bioorthogonal Pretargeting Therapeutics in PSMA-Positive
Prostate Cancer. Mol Pharm 17, 98-108
22. Hu, Y., He, Z., Hao, Y., Gong, L., Pang, M., Howard, G. P., Ahn, H. H., Brummet, M., Chen, K., Liu, H.
W., Ke, X., Zhu, J., Anderson, C. F., Cui, H., Ullman, C. G., Carrington, C. A., Pomper, M. G., Seo, J. H.,
Mittal, R., Minn, I., and Mao, H. Q. (2019) Kinetic Control in Assembly of Plasmid DNA/Polycation
Complex Nanoparticles. ACS Nano 13, 10161-10178
21. Banerjee, S. R., Kumar, V., Lisok, A., Chen, J., Minn, I., Brummet, M., Boinapally, S., Cole, M., Ngen, E.,
Wharram, B., Brayton, C., Hobbs, R. F., and Pomper, M. G. (2019) (177)Lu-labeled low-molecular-weight
agents for PSMA-targeted radiopharmaceutical therapy. Eur J Nucl Med Mol Imaging 46, 2545-2557
20. Peters, M. E., Rahman, S., Coughlin, J. M., Pomper, M. G., and Sair, H. I. (2020) Characterizing the Link
Between Glial Activation and Changed Functional Connectivity in National Football League Players Using
Multimodal Neuroimaging. J Neuropsychiatry Clin Neurosci 32, 191-195
19. Rowe, S. P., Solnes, L. B., Yin, Y., Kitchen, G., Lodge, M. A., Karakatsanis, N. A., Rahmim, A., Pomper,
M. G., and Leal, J. P. (2019) Imager-4D: New Software for Viewing Dynamic PET Scans and Extracting
Radiomic Parameters from PET Data. J Digit Imaging 32, 1071-1080
18. Paller, C. J., Piana, D., Eshleman, J. R., Riel, S., Denmeade, S. R., Isaacsson Velho, P., Rowe, S. P.,
Pomper, M. G., Antonarakis, E. S., Luo, J., and Eisenberger, M. A. (2019) A pilot study of prostatespecific
membrane antigen (PSMA) dynamics in men undergoing treatment for advanced prostate cancer. Prostate 79, 1597-1603
17. Werner, R. A., Thackeray, J. T., Pomper, M. G., Bengel, F. M., Gorin, M. A., Derlin, T., and Rowe, S. P.
(2019) Recent Updates on Molecular Imaging Reporting and Data Systems (MI-RADS) for Theranostic
Radiotracers-Navigating Pitfalls of SSTR- and PSMA-Targeted PET/CT. J Clin Med 8
16. Minn, I., Huss, D. J., Ahn, H. H., Chinn, T. M., Park, A., Jones, J., Brummet, M., Rowe, S. P., Sysa-Shah,
P., Du, Y., Levitsky, H. I., and Pomper, M. G. (2019) Imaging CAR T cell therapy with PSMA-targeted
positron emission tomography. Sci Adv 5, eaaw5096
15. Lesniak, W. G., Mease, R. C., Chatterjee, S., Kumar, D., Lisok, A., Wharram, B., Kalagadda, V. R.,
Emens, L. A., Pomper, M. G., and Nimmagadda, S. (2019) Development of [(18)F]FPy-WL12 as a PDL1
Specific PET Imaging Peptide. Mol Imaging 18, 1536012119852189
14. Song, X., Walczak, P., He, X., Yang, X., Pearl, M., Bulte, J. W. M., Pomper, M. G., McMahon, M. T., and
Janowski, M. (2016) Salicylic acid analogues as chemical exchange saturation transfer MRI contrast
agents for the assessment of brain perfusion territory and blood-brain barrier opening after intra-arterial
infusion. J Cereb Blood Flow Metab 36, 1186-1194
13. Werner, R. A., Bundschuh, R. A., Bundschuh, L., Lapa, C., Yin, Y., Javadi, M. S., Buck, A. K., Higuchi,
T., Pienta, K. J., Pomper, M. G., Lodge, M. A., Gorin, M. A., and Rowe, S. P. (2020) Semiquantitative
Parameters in PSMA-Targeted PET Imaging with [(18)F]DCFPyL: Impact of Tumor Burden on Normal
Organ Uptake. Mol Imaging Biol 22, 190-197
12. Sahakyan, K., Li, X., Lodge, M. A., Werner, R. A., Bundschuh, R. A., Bundschuh, L., Kulkarni, H. R.,
Schuchardt, C., Baum, R. P., Pienta, K. J., Pomper, M. G., Ross, A. E., Gorin, M. A., and Rowe, S. P.
(2020) Semiquantitative Parameters in PSMA-Targeted PET Imaging with [(18)F]DCFPyL: Intrapatient
and Interpatient Variability of Normal Organ Uptake. Mol Imaging Biol 22, 181-189
11. Coughlin, J. M., Horti, A. G., and Pomper, M. G. (2019) Opportunities in precision psychiatry using PET
neuroimaging in psychosis. Neurobiol Dis 131, 104428
10. Gomez, E., Tran, P. T., Pienta, K. J., Pomper, M. G., Gorin, M. A., and Rowe, S. P. (2019) Hereditary
Spherocytosis Presenting as Diffuse Bone Marrow Activation and Splenomegaly on PSMA-Targeted
18F-DCFPyL PET/CT. Clin Nucl Med 44, e313-e314
9. Reyes, D. K., Demehri, S., Werner, R. A., Pomper, M. G., Gorin, M. A., Rowe, S. P., and Pienta, K. J.
(2019) PSMA-targeted [(18)F]DCFPyL PET/CT-avid lesions in a patient with prostate cancer: Clinical
decision-making informed by the PSMA-RADS interpretive framework. Urol Case Rep 23, 72-74
8. Horti, A. G., Naik, R., Foss, C. A., Minn, I., Misheneva, V., Du, Y., Wang, Y., Mathews, W. B., Wu, Y.,
Hall, A., LaCourse, C., Ahn, H. H., Nam, H., Lesniak, W. G., Valentine, H., Pletnikova, O., Troncoso, J.
C., Smith, M. D., Calabresi, P. A., Savonenko, A. V., Dannals, R. F., Pletnikov, M. V., and Pomper, M.
G. (2019) PET imaging of microglia by targeting macrophage colony-stimulating factor 1 receptor (CSF1R). Proc Natl Acad Sci U S A 116, 1686-1691
7. Coughlin, J. M., Yang, T., Rebman, A. W., Bechtold, K. T., Du, Y., Mathews, W. B., Lesniak, W. G., Mihm,
E. A., Frey, S. M., Marshall, E. S., Rosenthal, H. B., Reekie, T. A., Kassiou, M., Dannals, R. F., Soloski, M. J., Aucott, J. N., and Pomper, M. G. (2018) Imaging glial activation in patients with post-treatment Lyme disease symptoms: a pilot study using [(11)C]DPA-713 PET. J Neuroinflammation 15, 346
6. Kumar, D., Lisok, A., Dahmane, E., McCoy, M., Shelake, S., Chatterjee, S., Allaj, V., Sysa-Shah, P.,
Wharram, B., Lesniak, W. G., Tully, E., Gabrielson, E., Jaffee, E. M., Poirier, J. T., Rudin, C. M., Gobburu,
J. V., Pomper, M. G., and Nimmagadda, S. (2019) Peptide-based PET quantifies target engagement of
PD-L1 therapeutics. J Clin Invest 129, 616-630
5. Werner, R. A., Thackeray, J. T., Pomper, M. G., Bengel, F. M., Gorin, M. A., Derlin, T., and Rowe, S. P.
(2019) Recent Updates on Molecular Imaging Reporting and Data Systems (MI-RADS) for Theranostic
Radiotracers-Navigating Pitfalls of SSTR- and PSMA-Targeted PET/CT. J Clin Med 8
4. Kumar, D., Lisok, A., Dahmane, E., McCoy, M., Shelake, S., Chatterjee, S., Allaj, V., Sysa-Shah, P.,
Wharram, B., Lesniak, W. G., Tully, E., Gabrielson, E., Jaffee, E. M., Poirier, J. T., Rudin, C. M., Gobburu,
J. V., Pomper, M. G., and Nimmagadda, S. (2019) Peptide-based PET quantifies target engagement of
PD-L1 therapeutics. J Clin Invest 129, 616-630
3. Foss, C. A., Kulik, L., Ordonez, A. A., Jain, S. K., Michael Holers, V., Thurman, J. M., and Pomper, M. G.
(2019) SPECT/CT Imaging of Mycobacterium tuberculosis Infection with [(125)I]anti-C3d mAb. Mol
Imaging Biol 21, 473-481
2. Foss, C. A., Plyku, D., Ordonez, A. A., Sanchez-Bautista, J., Rosenthal, H. B., Minn, I., Lodge, M. A.,
Pomper, M. G., Sgouros, G., and Jain, S. K. (2018) Biodistribution and Radiation Dosimetry of (124)IDPA-
713, a PET Radiotracer for Macrophage-Associated Inflammation. J Nucl Med 59, 1751-1756
1. Zukotynski, K. A., Valliant, J., Benard, F., Rowe, S. P., Kim, C. K., Pomper, M. G., and Cho, S. Y. (2018)
Flare on Serial Prostate-Specific Membrane Antigen-Targeted 18F-DCFPyL PET/CT Examinations in
Castration-Resistant Prostate Cancer: First Observations. Clin Nucl Med 43, 213-216
Book Chapters
5. Rowe, S. P., Werner, R. A., Garg, T., Gafita, A., Voter, A. F., Sadaghiani, M. S., Markowski, M. C., Paller,
C. J., Zalutsky, M. R., Solnes, L. B., Pomper, M. G. Small molecule vectors for endoradiotherapy. In:
Lewis, J. S., Bodei, L., Zeglis, B. M., eds. Endoradiotherapy. New York, NY: Springer, in press
​
4. Rowe SP, Pomper MG. Molecular imaging in oncology: Current impact and future directions. CA Cancer
J Clin. 2022 Jul;72(4):333-352. doi: 10.3322/caac.21713.
​
​3. Solnes, L. B., Jacobs, A. H., Coughlin, J. M., Du, Y., Goel, R., Hammoud, D. A., Pomper, M. G. (2020)
Central Nervous System Molecular Imaging. In: Ross, B. D., Gambhir, S. S., eds. Molecular Imaging
Principles and Practice. Shelton, CT: People’s Medical Publishing House, in press
​
2. Rowe, S. P., Sadaghiani, M. S., Werner, R. A., Higuchi, T., Derlin, T., Solnes, L. B., Pomper, M. G. (2020)
Prostate Cancer Theranostics. In: Ross, B. D., Gambhir, S. S., eds. Molecular Imaging Principles and
Practice. Shelton, CT: People’s Medical Publishing House, in press
​
1. Nimmagadda, S., Shelake, S., Pomper, M. G. (2019) Preclinical experimentation in oncology. In: Lewis,
J. S., Windhorst, A. D., Zeglis, B. M., eds. Radiopharmaceutical Chemistry. New York: Springer
​