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Auto-PERCIST is a software application which implements and automates the algorithms and techniques described by the PERCIST v1.0 criteria for the quantitative analysis and response assessment using [18F]FDG PET imaging. Through the implementation of these techniques, it performs an automated quantitative analysis of those regions of statistically significant elevated avidity, allowing the user to select those regions which are disease and storing the results of that analysis in database for comparison with future results and the automated determination of treatment response.

The software has been written in the Java language and is packaged to run on the Windows environment and integrate with freely available DICOM archives and SQL databases. Execution requires a license which is freely available to researchers.